Skin Diseases That Start With L

Skin Diseases That Start With L

Our focus for today is on the skin diseases that start with L.

Our skin is the largest organ in the body and is responsible for protecting us from environmental toxins, pathogens, and other harmful agents. Unfortunately, this protective barrier can become compromised, leading to the development of various skin diseases. These conditions can range from mild irritation and discoloration to debilitating and disfiguring diseases that can significantly impact a person’s quality of life. Common skin diseases include acne, dermatitis, psoriasis, and skin cancer, among others.

I approached the task of creating a complete skin disease list by carefully investigating each letter of the alphabet and researching which conditions were associated with them. This approach allowed me to curate a thorough collection of skin ailments.

So, let’s begin exploring this list of skin diseases starting with L!


85 Skin Diseases That Start With L

And here’s the list of skin diseases that begin with L letter.

Larva Currens

Larva Currens is an extremely itchy skin disease caused by an intestinal parasite that is transmitted to humans through contaminated soil. The disease spreads rapidly and can cause severe scarring if not treated promptly. Symptoms include red, raised, and winding linear lesions on the skin that move up to 10 cm per hour.

Loop Mark

Loop Mark is a temporary skin indentation caused by the pressure exerted by a surgical tool during a tissue biopsy. The mark typically disappears within a few hours, but in rare cases, it can lead to permanent scarring. Patients are advised to massage the affected area lightly to speed up the healing process.

Lofgren Syndrome

Lofgren Syndrome is a rare inflammatory condition that usually affects the lungs, lymph nodes, and joints. It is marked by symptoms such as fever, cough, and joint pain. The disease is typically resolved without complications within six months with proper treatment, mostly involving corticosteroids.

Ludwig’s Angina

Ludwig’s Angina is a bacterial infection of the mouth and neck that spreads rapidly and can be life-threatening if not treated promptly. Symptoms include severe swelling of the soft tissues of the neck and face, difficulty swallowing and breathing, and infections that spread to the chest.

Lymphomatoid Granulomatosis

Lymphomatoid granulomatosis is a rare type of non-Hodgkin’s lymphoma that attacks the skin, lungs, and brain. It typically presents with multiple nodules or tumors that grow slowly over time, eventually forming ulcerated and inflamed skin. Treatment involves a combination of chemotherapy and radiation therapy.


Leukoderma is a condition in which patches of skin become lighter than the surrounding skin due to loss of pigment. The disease is more prevalent in people who have autoimmune disorders or a family history of vitiligo. There is no cure for leukoderma, but treatment options like topical creams, light therapy or camouflage makeup can help reduce the visual symptoms.

Lichenoid Dermatitis

Lichenoid dermatitis is a chronic skin disease that produces an itchy rash with small, flat, livery papules that spread across the skin’s surface. It often appears in people who have previous viral infections or exposure to certain drugs. Treatment involves avoiding the triggering factor and sometimes corticosteroids.


Leprosy is a chronic bacterial infection that primarily affects the skin, eyes, nose, and peripheral nerves. It causes lesions, numbness, and muscle weakness. The disease is transmitted from person to person via nasal discharges, but only a small fraction of people with long-term exposure to the bacteria will contract it. Treatment involves a combination of antimicrobials and immune modulators.

Longitudinal Melanonychia

A dark band on the nail that progresses from the base of the nail to the tip and in rare instances may be a sign of melanoma, but most often the pigmentation is benign.


Leukonychia is a condition that causes white discoloration or spots on the nails. Some potential causes include injury, dietary deficiencies, and fungal infections. The condition is usually harmless, but if it persists, it may indicate an underlying health condition.

Lichenoid Keratosis

Lichenoid keratosis is a non-cancerous growth on the skin that resembles a wart or basal cell carcinoma. It is usually found in people with fair skin and history of sun exposure, appearing as a slightly raised, scaly lesion with a central indentation. Treatment typically involves surgical removal or cryotherapy.

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Livedo Racemosa

Livedo racemosa is a condition in which the skin takes on a net-like or lace-like pattern. It is mostly due to blockages or damage to the small blood vessels in the skin, usually due to autoimmune disorders, cold exposure or medication usage. The condition can sometimes lead to serious complications such as stroke and aneurysm and should be evaluated by a physician.


Lanolin-Induced allergic contact dermatitis is possible, especially in people with sensitive skin, who may develop an itchy, red rash in response to exposure to lanolin-containing products. The rash typically involves the hands, face, or neck and usual treatment includes avoiding the substance or products containing it.

Lupus Erythematosus

Lupus erythematosus is an autoimmune disease that causes inflammation of various parts of the body, including the skin, joints and internal organs. Skin lesions develop as a butterfly rash across nose and cheeks that worsen with sun exposure, but lupus can also present as other rashes or lesions. Treatment usually involves treating the underlying autoimmune condition and manages symptoms.

Lichen Planopilaris

Lichen Planopilaris is a variant of lichen planus that causes a scarring alopecia, leading to permanent hair loss on the scalp. The condition often causes a red, scaly rash that is intensely itchy and painful in advanced cases. Treatment involves preventing further hair loss with topical or systemic immunosuppressants and hair transplantation.

Lentigo Simplex

Lentigo Simplex is a non-cancerous growth on the skin that occurs in sun-exposed areas like the face, arms, and legs. It often appears as small, flat, dark spots that sometimes multiply into groups. Treatment is usually unnecessary but sometimes mistaken for malignant melanoma, so biopsy is recommended.

Lennert Lymphoma

Lennert lymphoma is an uncommon type of non-Hodgkin’s lymphoma that arises mainly in the skin. It is characterized by the growth of tumor cells that are large and closely packed in the skin, leading to reddish raised nodules or tumors. Treatment is determined by stage but usually involves radiation or chemotherapy.

Livedo Reticularis

Livedo Reticularis is a mottled skin rash associated with immune disorders, medication usage, or cold temperatures. It presents as a reddish-blue lace-like pattern on the skin, usually on the arms or legs. The rash may have a transient character and can resolve spontaneously but can also indicate serious medical conditions that require evaluation.

Leiner’s Disease

Leiner’s disease is an inherited immune deficiency disorder that primarily affects infants. It often appears in the first month of life and makes the skin thick and “sweaty.” The condition can produce other inflammatory symptoms like feeding problems that respond to antimicrobial therapy.

Lupus vulgaris

Lupus vulgaris is a chronic and progressive form of tuberculosis that affects the skin and occasionally other organs. It is characterized by reddish-brown plaques on the skin that gradually enlarge and ulcerate. Lupus vulgaris is caused by Mycobacterium tuberculosis, the bacterium responsible for tuberculosis, and is more common in individuals with weakened immune systems.


Lepidopterism is a skin condition caused by exposure to butterfly or moth scales or hairs. The condition is characterized by a rash, redness, and itching. People who handle butterflies or moths as part of their work or hobbies are at risk of developing lepidopterism. In severe cases, the condition can lead to respiratory symptoms and anaphylaxis.

Legius syndrome

Legius syndrome is a rare genetic disorder that affects the skin and other organs. It is characterized by café-au-lait macules, which are brown spots on the skin, and other symptoms such as learning difficulties and behavioral problems. The condition is caused by mutations in the SPRED1 gene, which regulates cell growth and division.

Lupoid rosacea

Lupoid rosacea is a chronic inflammatory condition that affects the skin on the face. It is characterized by acne-like papules and pustules, as well as redness and flushing. The condition can be mistaken for acne or rosacea. Lupoid rosacea is treated with topical and oral antibiotics, as well as topical steroids.


Lymphangiomatosis is a rare disorder that affects the lymphatic system, causing the formation of benign tumors made up of lymphatic vessels. The tumors can occur in the skin or other organs such as the spleen or lungs. Symptoms include swelling and pain in affected areas. Treatment depends on the severity of symptoms, and may involve surgery or medication.


Lhermitte’s sign is a neurological symptom that can be associated with a number of conditions, including multiple sclerosis, spinal cord injury, and vitamin B12 deficiency. It is characterized by a sudden electric shock-like sensation that runs down the back and into the arms or legs when the head is moved. The symptom is caused by damage to the myelin sheath that surrounds nerve fibers.

Leopard skin

Leopard skin is a pattern of skin discoloration that resembles the spots on a leopard. The condition can be caused by a number of factors, including sun exposure, medication, or underlying medical conditions such as Addison’s disease. Treatment for leopard skin depends on the underlying cause and may include topical or oral medications or lifestyle changes.

Lentigo maligna

Lentigo maligna is a type of skin cancer that is most common in older adults. It is characterized by a flat or slightly raised lesion on the skin that is usually irregular in shape and color. The lesion is usually found on areas of the skin that have been exposed to the sun. Treatment options for lentigo maligna include surgery, radiation therapy, and topical medications.

Lichen planus

Lichen planus is a common skin condition that is characterized by itchy, flat-topped papules and plaques on the skin. The condition can also affect the nails, scalp, and mucous membranes. The cause of lichen planus is not known, but it may be related to an autoimmune reaction. Treatment may involve topical or oral medications, as well as lifestyle changes.

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Lizard skin

Lizard skin is a term used to describe dry, scaly, and rough skin. The condition may be caused by a number of factors, including aging, genetics, or underlying medical conditions such as eczema or psoriasis. Treatment for lizard skin may include topical moisturizers and emollients, as well as lifestyle changes such as avoiding hot baths and using gentle cleansers.

Lacquer dermatitis

Lacquer dermatitis is a type of contact dermatitis that is caused by exposure to lacquer products such as nail polish or furniture finish. Symptoms include itching, redness, and blistering of the skin. Treatment may involve avoiding further exposure to the offending product and using topical or oral medications to alleviate symptoms.


Lipodermatosclerosis is a skin condition that affects the lower legs and is associated with chronic venous insufficiency. The condition is characterized by skin thickening and hardening, as well as pain and ulceration. Treatment may involve compression stockings, lifestyle changes, and topical or oral medications.

Lichen sclerosus

Lichen sclerosus is a chronic skin condition that primarily affects the genital and anal regions. The condition is characterized by white, shiny patches of skin that are itchy and painful. In severe cases, scarring and deformation of the affected areas can occur. Treatment may involve topical or oral steroids, as well as lifestyle changes.

Lassa fever

Lassa fever is a viral illness that is transmitted by contact with the urine or feces of infected rodents. The condition is characterized by fever, muscle aches, and bleeding from the gums, nose, or mouth. In severe cases, Lassa fever can lead to organ failure and death. Treatment may involve antiviral medications and supportive care.


Listeriosis is a bacterial infection that is caused by the bacterium Listeria monocytogenes. The condition is usually contracted by consuming contaminated food products such as unpasteurized dairy or meat products. Symptoms include fever, muscle aches, and gastrointestinal symptoms. In severe cases, Listeriosis can lead to meningitis or sepsis. Treatment may involve antibiotics and supportive care.

Lymphomatoid papulosis

Lymphomatoid papulosis is a rare skin condition that is characterized by the development of recurring lesions on the skin that resemble lymphoma. The condition is benign, but is associated with an increased risk of developing lymphoma. Treatment may involve topical or oral medications, as well as regular monitoring for signs of lymphoma.

Lightning burn

Lightning burns are injuries caused by lightning strikes. The burns are usually shallow and located on the skin as well as the internal organs. Most people struck by lightning survive, but may experience long-term symptoms such as memory loss, headaches, and sleep disturbances. Treatment may involve wound care and supportive care for any associated symptoms.

Lichen scrofulosorum

Lichen scrofulosorum is a rare form of lichen that is associated with tuberculosis. The condition is characterized by small, red-brown papules on the skin that usually occur on the trunk or limbs. Treatment includes addressing the underlying tuberculosis infection, as well as topical or oral medications to alleviate symptoms.


Loaiasis is caused by the parasitic worm Loa loa and is transmitted through the bites of infected deer flies or mango flies. Symptoms include painful swelling in the arms, legs, and face.

Lipoatrophia semicircularis

Lipoatrophia semicircularis is a rare, self-limiting condition that causes asymmetrical depression of subcutaneous adipose tissue. It is most commonly seen in young females and typically resolves on its own without treatment.

Lymphogranuloma venereum

Lymphogranuloma venereum is a sexually transmitted disease caused by the bacterium Chlamydia trachomatis. Symptoms include swollen lymph nodes, genital ulcers or blisters, and painful bowel movements.


Liposarcoma is a rare type of cancer that arises in fat cells. It can occur anywhere in the body but is most commonly found in the limbs, retroperitoneum, and the abdomen. Treatment may involve surgery, radiation therapy, and chemotherapy.


Latrodectism is a medical condition caused by the bite of black widow spiders. Symptoms include severe muscle pain, spasms, and abdominal cramping. In severe cases, it can lead to respiratory failure and death.

Lafora disease

Lafora disease is a rare genetic disorder that causes the accumulation of abnormal glycogen deposits in the body. Symptoms may include seizures, progressive cognitive decline, and loss of coordination.

Lelis syndrome

Lelis syndrome is a rare inherited disorder that affects the skin, hair, and nails. Symptoms may include reddish-brown skin lesions, brittle hair and nails, and an increased risk of skin cancer.

Linear porokeratosis

Linear porokeratosis is a type of skin disorder that is characterized by the development of hyperkeratotic plaques in a linear distribution. It usually affects the limbs and trunk and can be associated with an increased risk of skin cancer.

Lepromatous leprosy

Lepromatous leprosy is the most severe form of leprosy, caused by the bacteria Mycobacterium leprae. Symptoms include skin lesions, nerve damage, and muscle weakness.

Leech bite

Leech bites are small, circular wounds caused by the attachment of leeches to the skin. They can lead to bleeding and may cause infection if not cleaned properly.

Longitudinal erythronychia

Longitudinal erythronychia is a condition where the nails develop red or brown longitudinal lines that extend from the base to the tip. It can be caused by a variety of underlying conditions, including infections and tumors.

Leukemia cutis

Leukemia cutis is a rare skin manifestation of leukemia that presents in the form of erythematous or infiltrative plaques, papules, or nodules. It is most commonly seen in patients with acute myeloid leukemia.

Linear scleroderma

Linear scleroderma is a rare type of localized scleroderma that affects the skin and underlying tissues in a linear pattern. Symptoms include skin thickening, joint contractures, and muscle weakness.

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Lipschutz ulcer

Lipschutz ulcer is a rare, painful ulcer that occurs on the genitals as a result of a viral or bacterial infection. It is most commonly seen in young women and typically resolves on its own without treatment.

Lymphoma cutis

Lymphoma cutis is a rare form of non-Hodgkin’s lymphoma that affects the skin. It usually presents as erythematous, nodular or infiltrative lesions that can be mistaken for other skin diseases.

Levamisole-induced vasculitis

Levamisole-induced vasculitis is a rare autoimmune disorder that can occur after exposure to levamisole-contaminated cocaine. Symptoms can include skin lesions, joint pain, and blood vessel damage.

Lichen nitidus

Lichen nitidus is a type of skin rash that appears as small, flesh-colored bumps on the skin. It is most commonly seen in children and typically resolves on its own without treatment.

Localized lipodystrophy

Localized lipodystrophy is a rare disorder characterized by the loss of subcutaneous fat in specific areas of the body, usually the limbs and face. It can be caused by a variety of factors, including trauma and autoimmune disorders.

Lipoatrophia annularis

Lipoatrophia annularis is a rare skin condition that causes the loss of subcutaneous fat in a ring-shaped pattern. It can be associated with other autoimmune disorders, such as lupus erythematosus.

Lipoid proteinosis

Lipoid proteinosis is a rare genetic disorder that affects the skin, mucous membranes, and sometimes other internal organs. Symptoms may include thickening and scarring of the skin and vocal cords.

Lichen spinulosus

Lichen spinulosus is a benign skin condition that causes the development of spiny, cone-shaped bumps on the skin. It often affects the arms, legs, and trunk and typically does not require treatment.


Lobomycosis is a rare skin disease caused by the fungus Lacazia loboi. It typically presents as nodules or plaques on the skin that can become ulcerated and infected.


Lymphedema is a condition that occurs when excess fluid accumulates in the tissues due to damage or obstruction of the lymphatic system. Symptoms may include swelling, discomfort, and an increased risk of infection.

Lichen striatus

Lichen striatus is a self-limiting skin disorder that typically affects children and causes the development of pink, scaly patches on the skin. It usually resolves on its own without treatment.

Lichen amyloidosis

Lichen amyloidosis is a type of skin disorder that causes the development of itchy, dark-brown patches on the skin. It can be associated with chronic scratching and is more common in certain ethnic groups.


Lipoma is a benign tumor composed of adipose tissue. It typically presents as a soft, painless lump under the skin and usually does not require treatment unless it is causing discomfort or aesthetic concerns.


Small dilatations or enlargements of lymphatic vessels that cause skin to appear red, raised, and thickened.


White or gray patches inside the mouth which cannot be rubbed off. It is strongly associated with smoking, and can lead to oral cancer if left untreated.

Linea nigra

A vertical line that appears on the pregnant belly, from the pubic bone to the belly button. It is caused by hormonal changes during pregnancy.

LIG4 syndrome

A genetic disorder that impairs DNA repair and can lead to severe growth retardation, failure to thrive, and an increased risk of cancer.

Lichenoid trikeratosis

A benign skin condition in which small, rough, scaly papules develop on the skin. It is most commonly found on the arms and legs of middle-aged and elderly individuals.

Lamellar ichthyosis

A rare genetic skin disorder that causes the skin to become very dry, thick, and scaly. It can significantly impact a person’s quality of life.

Lupus pernio

A form of cutaneous lupus that leads to reddish-purple bumps or nodules on the skin, most commonly on the nose, cheeks, ears, and fingers.

Livedoid vasculopathy

A skin condition that causes painful ulcers on the legs, feet, and ankles. It is caused by problems with blood flow in the skin.

Lupoid sycosis

A chronic skin condition characterized by pustules, crusting, and hair loss around the mouth and chin. It is caused by a bacterial infection.


A rare type of cancer that affects the smooth muscle cells in the body. It can occur in any part of the body, including the skin.


A skin condition caused by the bite of a brown recluse spider, which can cause significant tissue damage and sometimes lead to death.

Lipedematous alopecia

A rare disorder characterized by hair loss and swelling of the scalp, face, and neck. It is often associated with an underlying autoimmune or metabolic disorder.

Lyme disease

A bacterial infection transmitted to humans by tick bites. It can cause a variety of symptoms, including a rash, fever, joint pain, and fatigue.


A bacterial infection that can be transmitted to humans through contact with water or soil contaminated with the urine of infected animals. It can lead to a variety of symptoms, including fever, chills, headache, and muscle aches.

Lymphedema praecox

A swelling of the arms or legs caused by a blockage in the lymphatic system. It can be caused by a congenital abnormality or damage to the lymphatic system, such as from surgery or cancer treatment.


A condition in which excessive consumption of lycopene, a nutrient found in tomatoes, can lead to gastrointestinal problems, skin discoloration, and other symptoms.

Leschke syndrome

A genetic condition characterized by thick, scaly skin on the hands and feet, along with delayed development, intellectual disability, and seizures.

Livedoid dermatitis

A skin condition characterized by painful ulcers and patches of discolored skin. It is caused by problems with blood flow in the skin.

Linea alba

A white line that appears on the abdomen, running vertically from the belly button to the pubic bone. It is a natural part of the human anatomy and is not a sign of any underlying condition.

Lead poisoning

A condition caused by exposure to lead, which can cause a variety of symptoms including abdominal pain, headache, fatigue, and cognitive impairment.


A medical condition marked by the abnormal accumulation of fat in certain parts of the body, most commonly in the limbs or around the abdomen.

Lichen aureus

A rare skin condition characterized by reddish-brown, scaly patches on the skin. It most commonly affects the legs and is of unknown cause.

Wrapping Up

And that’s our list of L skin diseases.

To compile a complete list of skin diseases, I began with an alphabet-first method that involved researching and identifying a skin condition that starts with each letter. This way, no aspect of skin disease was left unexplored, and an exhaustive list was compiled.

In summary, skin diseases represent a broad category of medical conditions that cover everything from rashes and acne to serious autoimmune disorders. Treatment options will often depend on the cause and severity of the condition. While some skin diseases resolve on their own or respond well to over-the-counter creams, others may require prescription-strength medication, phototherapy, or surgery. To minimize the chances of developing skin diseases, individuals should adopt a healthy lifestyle that includes regular exercise, a balanced diet, and diligent skincare. Additionally, recognizing and avoiding potential irritants such as certain fabrics, harsh soaps, and extreme temperatures can also minimize the risks.

Hope this post on skin diseases beginning with L alphabet has been useful to you!