Diseases That Start With P

Diseases That Start With P

Diseases that start with P are in the spotlight for today’s post.

Diseases are a ubiquitous part of life and medical science. They are defined as any condition that impairs the normal functioning of the body or its organs, and can manifest in a variety of ways. From the common cold to cancer, diseases can range from mild to severe, acute to chronic, and infectious to non-infectious. The study of diseases is called pathology, and it involves understanding the causes, symptoms, diagnosis, and treatment of various ailments affecting humans and animals.

The process of creating a list of diseases that started with every alphabet required patience, an eye for detail, and an extensive knowledge of medical terms. I meticulously researched and reviewed each medical terminology to ensure that every disease was accurately categorized by the first letter of the name.

So, let’s begin exploring this list of diseases starting with P!


107 Diseases That Start With P

And here’s the list of diseases that begin with P letter.


Pseudoachondroplasia is a rare, genetic disorder that affects bone growth and development. It is characterized by short stature, joint pain, and joint deformities. The condition usually becomes apparent in childhood and progresses gradually over time. Although there is no cure for pseudoachondroplasia, early diagnosis and treatment can help manage symptoms and prevent complications.

Prolidase deficiency

Prolidase deficiency is a rare metabolic disorder that affects the body’s ability to break down certain proteins. The condition is characterized by a wide range of symptoms, including skin ulcers, intellectual disability, and joint and bone abnormalities. Treatment for prolidase deficiency usually involves a combination of dietary changes and medication to manage symptoms and prevent complications.


Paraplegia is a form of paralysis that affects the lower half of the body. It is most commonly caused by damage to the spinal cord and can result in a loss of sensation, movement, and bowel and bladder control. There is currently no cure for paraplegia, but treatment options such as physical therapy and assistive devices can help improve quality of life for those affected.

Post-infectious myocarditis

Post-infectious myocarditis is a condition that occurs when the heart muscle becomes inflamed after a viral or bacterial infection. Symptoms include chest pain, shortness of breath, and fatigue, and the condition can be life-threatening if left untreated. Treatment for post-infectious myocarditis typically involves medication to manage symptoms and prevent complications.

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Panic disorder

Panic disorder is a type of anxiety disorder characterized by sudden and intense feelings of fear and panic. These episodes can be triggered by a variety of factors and can be difficult to predict or control. Treatment for panic disorder usually involves a combination of therapy and medication to help manage symptoms and prevent future episodes.


Polyarthritis is a condition that causes inflammation and pain in multiple joints throughout the body. It can be caused by a variety of factors, including autoimmune disorders and infections. Treatment options for polyarthritis depend on the underlying cause of the condition but may include medication, physical therapy, and lifestyle changes.

Paratyphoid fever

Paratyphoid fever is a bacterial infection that causes fever, diarrhea, and abdominal pain. It is most commonly spread through contaminated food or water and is most prevalent in developing countries. Treatment for paratyphoid fever typically involves antibiotic medication, hydration, and rest.

Proliferating trichilemmal cyst

Proliferating trichilemmal cyst is a rare type of cyst that forms in the hair follicles on the scalp. It is characterized by a slow-growing, painless mass that can become quite large over time. Treatment for proliferating trichilemmal cysts usually involves surgical removal to prevent complications and ensure complete removal.

Pili canulati

Pili canulati is a rare hair disorder that causes the hair shaft to become thin and fragile. The condition can result in hair loss and skin irritation and is often difficult to manage. Treatment for pili canulati usually involves hair care and styling techniques to prevent further damage and promote healthy hair growth.

Primary agammaglobulinemia

Primary agammaglobulinemia is a genetic immune disorder that affects the body’s ability to produce antibodies. It is characterized by recurrent infections and can be life-threatening if left untreated. Treatment for primary agammaglobulinemia usually involves a combination of immunoglobulin replacement therapy and antibiotics to prevent and manage infections.

Purtilo syndrome

Purtilo syndrome is a rare immune disorder that affects the body’s ability to fight off infections. It is characterized by recurrent infections, autoimmune disorders, and other health issues. Treatment for Purtilo syndrome usually involves immunoglobulin replacement therapy and medication to manage symptoms and prevent complications.

Pentalogy of Cantrell

Pentalogy of Cantrell is a rare birth defect characterized by the incomplete development of the chest and abdominal wall. The condition can affect the heart, lungs, and other organs and can be life-threatening if left untreated. Treatment for Pentalogy of Cantrell usually involves surgery to correct the abnormalities and prevent complications.

Phosphoglucomutase deficiency

Phosphoglucomutase deficiency is a rare metabolic disorder that affects the body’s ability to process glycogen, a form of sugar. The condition is characterized by low blood sugar levels, muscle weakness, and other health issues. Treatment for phosphoglucomutase deficiency usually involves a combination of dietary changes and medication to manage symptoms and prevent complications.

Polycystic kidney disease

Polycystic kidney disease is a genetic disorder that affects the kidneys and can lead to chronic kidney failure. The condition is characterized by the growth of numerous cysts on the kidneys, which can cause pain, high blood pressure, and other health issues. Treatment for polycystic kidney disease usually involves medication, lifestyle changes, and eventually, dialysis or kidney transplant.

Progressive systemic sclerosis

Progressive systemic sclerosis, also known as scleroderma, is a rare autoimmune disorder that affects the skin and other organs. The condition is characterized by the hardening of the skin and connective tissue, as well as other symptoms such as joint pain and fatigue. Treatment for progressive systemic sclerosis typically involves medication, physical therapy, and other supportive measures to manage symptoms and prevent complications.


Perniosis, also known as chilblains, is a skin condition that causes red, itchy, and swollen skin on the fingers, toes, and other extremities. It is most commonly caused by exposure to cold and wet conditions and usually resolves on its own without treatment. However, in some cases, medication may be necessary to manage symptoms and prevent complications.

Protein C deficiency

Protein C deficiency is a rare blood disorder that affects the body’s ability to control blood clotting. The condition can cause recurrent blood clots, which can be life-threatening if left untreated. Treatment for protein C deficiency typically involves medication to prevent blood clots and other complications.

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Polydactyly is a genetic condition characterized by the presence of extra fingers or toes. The condition is often harmless and does not require treatment unless there are other associated health issues. In some cases, surgical removal may be necessary to prevent complications or improve function.

Progressive supranuclear palsy

Progressive supranuclear palsy is a rare neurodegenerative disorder that affects movement, cognition, and other bodily functions. The condition is characterized by symptoms such as difficulty with balance and coordination, speech and swallowing problems, and other health issues. There is currently no cure for progressive supranuclear palsy, but treatment can help manage symptoms and improve quality of life.

Pyridoxine deficit

Pyridoxine deficit is a rare form of vitamin B6 deficiency that can cause a range of health issues, including anemia, nervous system problems, and skin issues. Treatment for pyridoxine deficit usually involves vitamin B6 supplementation, as well as other supportive measures to manage symptoms and prevent complications.

Pseudovaginal perineoscrotal hypospadias

A rare condition where there is genital malformation in males.

Polycystic ovarian syndrome

A hormonal disorder in women leading to enlarged ovaries with small cysts.

Primary ciliary dyskinesia

A genetic disease where the cilia, responsible for moving fluid in the body, do not function properly.


A severe bacterial infection leading to the formation of abscesses in various organs of the body.


A genetic disease causing the body to age much faster than normal.

Primary malignant lymphoma

A type of cancer that starts in the lymphatic system.

Potassium aggravated myotonia

A genetic disorder affecting the muscles and causing them to contract and relax abnormally.

Pilonidal cyst

A cyst that develops at the base of the tailbone and can become infected.


A form of arthritis causing sudden joint pain and swelling due to calcium crystals forming in the joints.

Primary cutaneous amyloidosis

A rare condition where protein builds up in the skin, leading to itching and thickened skin.

Posterior valve urethra

A congenital abnormality in males where a “flap” of tissue causes an obstruction in the urethra.

Passive-aggressive personality disorder

A mental health condition characterized by a persistent pattern of passive resistance to authority and stubbornness.

Panayiotopoulos syndrome

A rare childhood epilepsy syndrome causing seizures with visual hallucinations and vomiting.

Portal vein thrombosis

A blood clot in the portal vein, which carries blood from the intestines to the liver.

Palmitoyl-protein thioesterase deficiency

A rare genetic disease causing a build-up of fatty material in the body’s cells and tissues.

Poikiloderma of Rothmund

A rare genetic skin disorder causing patches of skin to change color and age prematurely.

Partial lissencephaly

A rare brain malformation where the surface of the brain is unusually smooth and lacks the normal folds and creases.

Polymorphous low-grade adenocarcinoma

A slow-growing malignant tumor that most commonly occurs in the oral cavity.


A bacterial infection of the muscles causing fever, muscle pain and swelling.

Progressive diaphyseal dysplasia

A rare genetic bone disorder that causes abnormal growth and development of the long bones in the body.


A group of inherited disorders that affect the production of heme, a component of hemoglobin.


An inherited disorder where the body cannot break down phenylalanine, an amino acid found in many foods.

Penile agenesis

A rare congenital abnormality where the penis does not develop properly.

Peanut hypersensitivity

An allergic reaction to peanuts that can cause severe symptoms, including anaphylaxis.

Progressive multifocal leukoencephalopathy

A rare and often fatal brain infection caused by the JC virus.


An infectious disease caused by the Chlamydia psittaci bacteria, typically transmitted from birds to humans.

Pseudopelade of Brocq

A rare form of scarring hair loss affecting the scalp.

Primary orthostatic tremor

The person experiences involuntary shaking of their legs while standing.


Inflammation of the prostate gland causes frequent urination and pelvic pain.

Pterygium colli

Characterized by a web of skin extending from the neck to the shoulders.

Primary craniosynostosis

The early fusion of bones in an infant’s skull causes an abnormal head shape and brain growth issues.


Causes skin thickening and bone growth leading to enlarged extremities and facial features.

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Commonly known as whooping cough, this highly contagious respiratory disease causes severe coughing fits.

Pulmonary embolism

A blockage in the lungs due to a blood clot that travels from another part of the body can be life-threatening.


An impairment in the ability to recognize faces and recall associated memories.

Peters anomaly

Congenital eye disorder where the front part of the eye does not develop fully, causing vision problems or blindness.

Pancreatic cancer

Occurs when abnormal cells in the pancreas grow and divide, forming a tumor that can spread to other parts of the body.

Pulmonary valve stenosis

Narrowing of the pulmonary valve in the heart can lead to breathing difficulties and other complications.

Progressive external ophthalmoplegia

Rare genetic disorder resulting in muscle weakness and paralysis of the eyes and other muscles.


Infection or inflammation of the tissue lining the abdomen causes severe abdominal pain, fever, and other symptoms.


A bacterial infection spread by fleas that can cause severe illness and even death if left untreated.


A rare skeletal disorder causing shortened arms and legs, spinal abnormalities, and breathing difficulties.

Phocomelia syndrome

Birth defect causing underdeveloped or absent limbs and other physical abnormalities.

Pulmonary veno-occlusive disease

Rare disease that affects the blood vessels in the lungs, resulting in high blood pressure and difficulty breathing.

Pelvic inflammatory disease

Infection and inflammation of a woman’s reproductive organs can cause chronic pain and infertility.


Skin inflammation caused by exposure to plant sap and sunlight, resulting in a painful rash and blisters.

Pachyonychia congenita Jackson

Rare inherited disorder characterized by thick, abnormally shaped nails and other skin and dental abnormalities.


Autoimmune disease that causes inflammation of the blood vessels and can damage organs like the kidneys and lungs.

Perisylvian syndrome

A rare neurological disorder that affects language and speech capabilities.

Psychogenic polydipsia

Drinking excessive amounts of water due to a mental health condition can lead to electrolyte imbalances and other complications.

Primary muscular atrophy

A group of genetic disorders causing the gradual wasting away of muscle tissue and weakness.

Polycythemia vera

Blood disorder that leads to the overproduction of red blood cells, causing circulation problems and other complications.

Paroxysmal cold hemoglobinuria

A rare blood disorder that causes anemia and other symptoms when exposed to cold temperatures.

Phacomatosis pigmentokeratotica

A rare genetic disease causing skin pigmentation abnormalities and the development of benign tumors.

Pacman dysplasia

A rare skeletal disorder characterized by the underdevelopment or absence of bones in the arms and legs.

Pseudotumor cerebri

A condition where increased pressure in the skull causes severe headaches, vision problems, and other symptoms.


A chronic autoimmune condition affecting the skin and joints characterized by red, scaly patches.

Pick disease

A rare neurodegenerative disorder that causes progressive destruction of brain cells leading to dementia.

Pediatric T-cell leukemia

A type of leukemia that affects the T-cells, a type of white blood cell responsible for fighting infections.

Pemphigus vulgaris

A rare autoimmune disorder causing blistering of the skin and mucous membranes.

Platelet disorder

A group of disorders that affect the number or function of platelets, which are important for blood clotting.


Inflammation of the lining of the rectum, causing pain and discomfort.

Polydactyly postaxial

A genetic condition characterized by the presence of extra toes or fingers on the outside of the hand or foot.


A rare genetic disorder causing salt wasting and dehydration in infants.


A rare genetic disorder that prevents proper metabolism of phenylalanine, an amino acid found in many proteins.

Periventricular leukomalacia

A type of brain injury causing damage to the white matter surrounding the ventricles in premature infants.


A rare type of pancreatic cancer that most commonly affects children.


An anxiety disorder characterized by an intense fear and avoidance of childbirth.


An infection of the lungs that can be caused by bacteria, viruses, or other microorganisms.


An inflammatory condition affecting the muscles and causing weakness and sometimes pain.

Penoscrotal transposition

A rare congenital abnormality in which the penis is located on the scrotum instead of the perineum.

Pierre Robin sequence

A collection of congenital conditions that can cause a small lower jaw, cleft palate, and difficulty breathing.


An inherited blood disorder characterized by abnormally shaped red blood cells that can cause anemia.


A lung infection caused by the fungus Pneumocystis jirovecii that can occur in people with weakened immune systems.

Post-polio syndrome

A condition that can occur in survivors of polio many years after recovery, causing weakness and muscle atrophy.


A group of neurological disorders that cause movement problems including tremors, rigidity, and difficulty with balance.


An infection of the skin surrounding a nail, typically caused by bacteria or fungi.


A viral infection that can cause paralysis, particularly in children.

Placenta disorder

A condition affecting the placenta during pregnancy that can cause complications for both the mother and baby.

Pseudocholinesterase deficiency

An inherited condition that can affect how certain medications are metabolized, sometimes causing prolonged neuromuscular blockade.

Post-SSRI sexual dysfunction

An uncommon but potentially serious side effect of some antidepressant medications that can cause decreased libido and sexual dysfunction.


A fear or aversion to taking medications, often due to concerns about their safety or side effects.

Protein S deficiency

A genetic condition that can increase the risk of blood clots and thrombosis.

Processing disorder

A neurological condition that can affect the ability to process and interpret sensory information, leading to difficulty with language, behavior, and social skills.

Wrapping Up

And that’s our list of P diseases.

Compiling a list of diseases that began with every alphabet was a fascinating challenge for me. I approached this task by breaking it down by each alphabet. After thorough research, I categorized each condition by the letter, and then double-checked it with reputable medical sources to validate the correctness of every item.

The study of diseases highlights the importance of an integrated healthcare system aimed at combating them. This necessitates a coordinated approach between the government, NGO’s, medical professionals, and the individual in embracing healthy living practices as well as risk reduction strategies to combat the scourge of diseases.

Hope this post on diseases beginning with P alphabet has been useful to you!